Detalhe da pesquisa
1.
Membrane-bound mRNA immunogens lower the threshold to activate HIV Env V2 apex-directed broadly neutralizing B cell precursors in humanized mice.
Immunity
; 55(11): 2168-2186.e6, 2022 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36179690
2.
Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors.
Immunity
; 55(11): 2149-2167.e9, 2022 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36179689
3.
Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses.
Immunity
; 55(10): 1856-1871.e6, 2022 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35987201
4.
Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice.
Cell
; 166(6): 1445-1458.e12, 2016 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27610569
5.
Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches.
Immunity
; 46(6): 1073-1088.e6, 2017 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28636956
6.
HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.
Immunity
; 45(3): 483-496, 2016 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27617678
7.
One-step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock-in mice.
EMBO J
; 37(18)2018 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30087111
8.
PKA: lessons learned after twenty years.
Biochim Biophys Acta
; 1834(7): 1271-8, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23535202
9.
Structural basis for the regulation of protein kinase A by activation loop phosphorylation.
J Biol Chem
; 287(18): 14672-80, 2012 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22334660
10.
Phosphoryl transfer by protein kinase A is captured in a crystal lattice.
J Am Chem Soc
; 135(12): 4788-98, 2013 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23458248
11.
Optimization of an alum-anchored clinical HIV vaccine candidate.
NPJ Vaccines
; 8(1): 117, 2023 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37573422
12.
Global consequences of activation loop phosphorylation on protein kinase A.
J Biol Chem
; 285(6): 3825-3832, 2010 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19965870
13.
Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers.
Science
; 363(6427): 649-654, 2019 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30573546
14.
A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Science
; 366(6470)2019 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31672916
15.
Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding.
Nat Commun
; 8(1): 1655, 2017 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29162799
16.
Evolution of the eukaryotic protein kinases as dynamic molecular switches.
Philos Trans R Soc Lond B Biol Sci
; 367(1602): 2517-28, 2012 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22889904
17.
Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase.
J Mol Biol
; 422(2): 215-29, 2012 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22617327
18.
A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold.
J Mol Biol
; 415(4): 666-79, 2012 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22138346
19.
Domain characterization of a 4-alpha-glucanotransferase essential for maltose metabolism in photosynthetic leaves.
J Biol Chem
; 283(30): 20797-804, 2008 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-18499663
20.
The role of cytosolic alpha-glucan phosphorylase in maltose metabolism and the comparison of amylomaltase in Arabidopsis and Escherichia coli.
Plant Physiol
; 142(3): 878-89, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16980562